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A serial killer mutates with a chemical inside a sewer, to become a monster made of human waste just as the FBI and police are onto him.
Mad scientist Dr. Stern is turning students into super-smart cannibalistic zombies, and the local cops are too busy chasing a sex fiend to stop the flesh-eating ghouls. Fortunately, Stern's nemesis, FBI agent Susan Hannigan, is on the case. As the ravenous monsters overrun the town, Hannigan tries to convince Stern's faithful assistant to reveal how to foil the crazed doctor's evil scheme.
Waldo Williams returns from his Tijuana vacation to find out that he had become infected by the Notorious Mexican Butt Humping Bullfrog. After being diagnosed by his proctologist with just days to live, Waldo seeks the help of the mysterious Japanese specialist, Dr. Wansamsaki, who treats Waldo with his unorthodox methods, which involve a long nuclear rod. The next day, Waldo’s rear end starts glowing a bright green – and that’s only the beginning. Within days, Waldo’s rear end develops a mind of its own, becoming capable of breaking away in the middle of the night, committing a murÂder or two and then returning before morning, leaving a fecal trail that leads right to Waldo’s bedroom.
