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After their van breaks down by the side of the road, a group of hip teenagers seek shelter at an old lodge, where several go missing one by one.
A doctor—on orders from a sentient brain—kidnaps intimate couples and takes them to his mansion as prisoners. He injects his subjects with a substance to 'enhance' their sexual abilities. The curious doctor then forces his hostages to have sex. While they are making love, he drains a fluid from them, which he needs to prevent himself from transforming into a monster.
